翻訳と辞書 Words near each other ・ Mir-135 microRNA precursor family ・ Mir-137 ・ MiR-138 ・ Mir-14 microRNA precursor family ・ Mir-143 ・ MiR-144 ・ Mir-145 ・ MiR-146 ・ Mir-148/mir-152 microRNA precursor family ・ Mir-15 microRNA precursor family ・ MiR-150 ・ Mir-153 microRNA precursor family ・ Mir-154 microRNA precursor family ・ MiR-155 ・ Mir-156 microRNA precursor ・ Mir-16 microRNA precursor family ・ Mir-160 microRNA precursor family ・ Mir-166 microRNA precursor ・ Mir-17 microRNA precursor family ・ Mir-172 microRNA precursor family ・ Mir-181 microRNA precursor ・ Mir-184 ・ Mir-185 microRNA precursor family ・ Mir-186 microRNA precursor family ・ Mir-187 microRNA precursor family ・ Mir-188 microRNA precursor family ・ Mir-19 microRNA precursor family ・ Mir-190 microRNA precursor family ・ MiR-191 ・ Mir-192/215 microRNA precursor Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Mir-16 microRNA precursor family ： ウィキペディア英語版 Mir-16 microRNA precursor family The miR-16 microRNA precursor family is a group of related small non-coding RNA genes that regulates gene expression. miR-16, miR-15, mir-195 and miR-457 are related microRNA precursor sequences from the mir-15 gene family (()). This microRNA family appears to be vertebrate specific and its members have been predicted or experimentally validated in a wide range of vertebrate species ((MIPF0000006 )). ==Background== The human ''miR-16'' precursor was discovered through detailed expression profile and Karyotype analyses of patients by Calin and colleagues. Karyotyping of chromosome structures from individuals with B-cell chronic lymphocytic leukaemias (B-CLL) found that more than half have alterations in the 13q14 region.〔 Deletions of this well characterised 1 megabase region of the genome was also observed in approximately 50% of mantle cell lymphoma, up to 40% of multiple myeloma, and 60% of prostate cancers. Comprehensive screenings of the region at the time did not provide consistent evidence of involvement from any of the known genes at the time.〔〔 Using CD5+ B-lymphocytes, which is known to accumulate with B-CLL progression, the minimal region lost from 13q14 region was scrutinised for regulatory elements.〔 Publicly available sequence databases were used to identify a gene cluster which encodes the homologue to the human ''miR15'' and ''miR16'' from the ''Caenorhabditis elegans''. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Mir-16 microRNA precursor family」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.